Description
Kamagra (sildenafil)
Kamagra is a generic sildenafil manufactured by Ajanta Pharma in India. It contains the same active ingredient as Viagra and works identically. In India and many other markets, it’s a licensed generic. In the United States, the European Union, and the United Kingdom, Kamagra is not approved or licensed as a medicine — it can be ordered online, but it isn’t a product that has gone through the regulatory review process in those jurisdictions. This is worth knowing, not as a reason to dismiss it, but because counterfeit or adulterated versions circulate in the same online channels, and distinguishing genuine Ajanta product from fakes requires buying from verified sources.
Available in 50 mg and 100 mg tablets.
Dosing
The recommended dose for most patients is 50 mg, taken approximately one hour before sexual activity. If 50 mg is sufficient, there’s no reason to use 100 mg. If 50 mg doesn’t produce adequate effect, 100 mg is the next step — and the maximum. One dose per 24-hour period. Men with severe kidney or liver dysfunction should not exceed 25 mg without medical guidance.
Effects begin 30 to 60 minutes after taking the tablet, faster on an empty stomach, delayed by fatty food or alcohol. Duration: 4 to 6 hours.
How it works
Sildenafil inhibits PDE5, the enzyme that limits cyclic GMP availability in penile smooth muscle. Sexual stimulation releases nitric oxide, producing cyclic GMP, which relaxes smooth muscle and allows blood to fill the erectile tissue. Sildenafil prolongs that response. Without arousal, it has no visible effect — it’s not an aphrodisiac and doesn’t work independently of the physiological response to stimulation.
Nitrates
Kamagra/sildenafil combined with nitrates — nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, amyl nitrate — causes potentially fatal hypotension. This is absolute and applies regardless of dose or timing. If you take nitrates for any reason, sildenafil is not compatible.
Contraindications
All nitrates. Recent cardiovascular events or surgery with incomplete recovery. Uncontrolled hypertension. Blood disorders (leukemia, sickle cell anemia, myeloma) that predispose to priapism. Retinitis pigmentosa. Peyronie’s disease or penile deformities. Severe hepatic or renal impairment. Hypersensitivity to sildenafil.
Side effects
Headache, facial flushing, nasal congestion, nosebleed, nausea, upset stomach, and increased heart rate are the most commonly reported. Visual disturbances — blue tint, brightness sensitivity — reflect the drug’s effect on retinal PDE6. Significant blood pressure drops are possible, particularly when standing quickly.
Serious effects requiring same-day medical attention: chest pain, facial swelling, breathing difficulty, sudden vision loss, syncope.
Priapism — erection lasting more than 4 hours — is an emergency. Seek treatment immediately; delay causes irreversible damage.
Alcohol and grapefruit
Limit alcohol to three units maximum. More than that compounds vasodilation and makes hypotension more likely. Grapefruit juice inhibits sildenafil metabolism and raises blood levels unpredictably — avoid it on days you take the drug.
