Ivermectin

 

What is Ivermectin

Ivermectin works by paralyzing and killing parasites that affect the body, particularly those that cause infections in the intestinal tract, skin, and eyes. First discovered in the late 1970s, and FDA-approved as anti-parasitic medication, ivermectin has been used in both human and veterinary medicine for decades. This medication works by paralyzing and killing parasites that affect the body, particularly those that cause infections in the intestinal tract, skin, and eyes.

How Ivermectin Works

Ivermectin works by binding to specific channels in parasite nerve and muscle cells called glutamate-gated chloride channels. This binding causes increased permeability to chloride ions, leading to hyperpolarization of the cell membrane, paralysis, and death of the parasite. This mechanism makes ivermectin effective against various parasites while having minimal impact on human cells, which lack these specific channels.

Ivermectin used to treat infections caused by roundworms, threadworms, and other parasitic organisms. It’s particularly effective against river blindness (onchocerciasis), strongyloidiasis, and scabies. Ivermectin for scabies paralyzes the mites and prevents them from reproducing. For lice, ivermectin can be used topically to kill the parasites and their eggs. Ivermectin cream formulations like Soolantra (1% ivermectin) are specifically developed to treat rosacea, where the medication reduces inflammation and kills Demodex mites that may contribute to symptoms.

Interest in ivermectin and COVID-19 emerged during the pandemic, with some early in vitro studies showing potential antiviral effects. However, major health organizations including the FDA and WHO have stated that current evidence doesn’t support using ivermectin for COVID-19 outside clinical trials, as most well-designed studies haven’t shown significant clinical benefits in humans with COVID-19.

Ivermectin Dosage

Healthcare providers calculate ivermectin dosage for humans based on body weight, starting from 200 micrograms per kilogram (mcg/kg) .

For intestinal strongyloidiasis (threadworm infection) treatment the standard ivermectin dosage is a single oral dose of 200 mcg/kg of body weight. Some patients may require follow-up treatment 2 weeks after the initial dose if stool examination shows continued infection.

To treat onchocerciasis (river blindness), the ivermectin dosage for humans is also starts from 200 mcg/kg as a single oral dose, usually repeated every 6-12 months until the parasitic infection resolves. This treatment may continue for years in endemic areas to prevent reinfection.

For scabies infections, ivermectin dosage starts from 200 mcg/kg as a single oral dose, often with a second dose administered 1-2 weeks after the first to kill newly hatched mites. Some resistant cases may require additional doses or combination therapy with topical treatments.

Ivermectin dosage for humans for parasites may vary for less common conditions. For cutaneous larva migrans single dose of 200 mcg/kg was effective in most cases, though some patients required a second dose one week later.

Ivermectin cream for rosacea is applied as a thin layer containing 1% ivermectin once daily. Treatment usually continues for several weeks until improvement is seen, with many patients noticing results within 2-4 weeks.

If to use topical ivermectin for lice, the application instructions vary by product formulation, but involve applying the medication to dry hair, leave it on for a specified period (usually 10 minutes), and then rinse
thoroughly.

Ivermectin tablets manufactured for humans differ significantly from ivermectin paste or other veterinary formulations. The ingredients, dosage concentration, and inactive compounds in animal products are not intended for human consumption. Self-medicating with veterinary ivermectin can lead to serious health consequences including overdose, as these products are highly concentrated for large animals.

How to Take Ivermectin

Ivermectin tablets should be taken on an empty stomach with a full glass of water. For best absorption, take the medication at least 1 hour before a meal or 2 hours after eating. If you experience stomach upset, your doctor may recommend taking ivermectin with food.

Ivermectin pills come in 3mg and 6mg tablets. It’s important to take the exact number of tablets prescribed rather than estimating dosage.

Apply a pea-sized amount to each affected area of the face, avoiding the eyes and lips of ivermectin cream for skin conditions like rosacea. Wash your hands thoroughly before and after application. The cream should be applied at approximately the same time each day, in the evening.

Older adults should be monitored more closely for side effects and drug interactions, particularly if taking multiple medications.

Ivermectin for lice is applied to dry hair, left on for the recommended time (usually 10 minutes), and then rinsed out thoroughly. A fine-toothed comb may be needed to remove dead lice after treatment.

Excessive alcohol consumption should be avoided as it may increase the risk of side effects. Grapefruit juice, which affects the metabolism of many medications, has not been shown to significantly impact ivermectin.

For intestinal parasites, effects may begin within hours, while visible improvement in skin conditions like scabies typically takes days to weeks.

Ivermectin Side Effects

Common side effects that typically don’t require immediate medical attention include:

  • Dizziness or lightheadedness
  • Temporary skin rash or itching
  • Mild stomach discomfort, nausea, or diarrhea
  • Temporary joint or muscle pain
  • Headache
  • Swollen lymph nodes (especially in patients treating onchocerciasis)

Serious side effects that warrant medical attention include:

  • Severe skin reactions including blistering or peeling
  • Visual disturbances or eye pain
  • Rapid heartbeat or significant changes in blood pressure
  • Severe dizziness or fainting
  • Difficulty breathing or swallowing
  • Seizures or neurological symptoms

Patients may experience a reaction known as Mazzotti reaction as the parasites die. This reaction can include:

  • Fever and chills
  • Joint and muscle pain
  • Headache and dizziness
  • Swollen and tender lymph nodes
  • Rapid heartbeat
  • Skin rash and severe itching

Symptoms of ivermectin overdose may include:

  • Severe nausea, vomiting, and diarrhea
  • Low blood pressure
  • Ataxia (problems with balance and coordination)
  • Seizures or coma in severe cases
  • Visual hallucinations
  • Confusion or altered mental status

Topical ivermectin formulations may cause local reactions including:

  • Skin burning or stinging sensation
  • Dryness or flaking of the treated area
  • Increased redness or irritation
  • Contact dermatitis in sensitive individuals

Ivermectin Contraindications

Don’t use ivermectin if you are:

  • Allergic to ivermectin or any ingredients in the specific formulation
  • Pregnant or breastfeeding, unless specifically prescribed by your doctor after weighing risks and benefits
  • Taking medications that may interact with ivermectin, particularly certain blood thinners, some antipsychotic medications, or other drugs that affect GABA receptors
  • Suffering from liver disease or severe hepatic impairment
  • Diagnosed with conditions that affect the blood-brain barrier, which could increase risk of neurological side effects
  • Under 15 kg (33 lbs) in weight or under 5 years of age (for oral formulations)
  • Planning to use veterinary formulations of ivermectin, which have different ingredients and concentrations not safe for human use
  • Self-medicating for COVID-19, as this use is not approved by major health organizations

Special caution should be exercised when combining fenbendazole and ivermectin or other antiparasitic medications, as drug interactions may occur.

Ivermectin Generic Names

Iverheal – Manufactured by Healing Pharma in India, Iverheal contains ivermectin as its active ingredient and is available in 3mg, 6mg, and 12mg tablets. A package of 10 tablets typically costs $8-12, making it one of the more affordable generic options.

Iverjohn – Produced by John Lee Pharma in India, Iverjohn offers ivermectin tablets in 6mg and 12mg strengths. Known for consistent quality control, a package of 10 tablets ranges from $10-15 depending on dosage strength.

Iverscab – Manufactured by Mankind Pharma in India, Iverscab is primarily marketed for scabies treatment. Available in 6mg and 12mg tablets, a package of 10 tablets typically costs 12-16 Euro, slightly higher due to its targeted formulation.

Stromectol is widely recognized internationally. Manufactured by Merck (MSD) in various countries including India for export markets, it costs significantly more at $30-40for 10 tablets of 3mg strength.

How to Buy Ivermectin Online

In the United States, the legal status of ivermectin requires a prescription from a licensed healthcare provider. For those who wander where to buy ivermectin for humans online, there are several websites offering the medication without a prescription.

The ivermectin cost varies significantly between brand name and generic versions. Brand name Stromectol typically costs $35-50 per tablet in the US, making a course of 10 pills potentially cost $350-500. Generic ivermectin is substantially more affordable at approximately $3-8 per tablet, or $30-80 for 10 pills.

Delivery times for online purchases from online pharmacies range from 6-14 business days and depends on shipping method and location.

Some seek how to get ivermectin out veterinary formulations where ivermectin for sale is marketed for animals, this approach carries serious risks. Veterinary products have different concentrations, ingredients, and quality controls not intended for human consumption.

Megalis

What Is Megalis

Megalis, a popular generic version of tadalafil, belongs to the class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Megalis 20, manufactured by Macleods Pharmaceuticals in India, contains the same active ingredient as the brand-name medication Cialis, with identical molecular structure and pharmacological effects.

Megalis Mechanism of Action

Megalis active ingredient tadalafil selectively inhibits phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. When sexual stimulation occurs, nitric oxide is released into the erectile tissue and activate the enzyme guanylate cyclase. This enzyme increases levels of cGMP, which relaxes smooth muscles and increases blood flow to specific areas of the penis. By blocking PDE5, megalis 20mg allows cGMP to accumulate and persist longer, maintains the relaxation of smooth muscle in the penis and sustains increased blood flow. Megalis 10 can begin working within 30 minutes and maintain effectiveness for up to 36 hours.

Megalis Dosage

Megalis comes in megalis 10 and megalis 20 mg. The starting dose is megalis 10 mg taken at least 30 minutes before sexual activity. Dosage can be adjusted to megalis 20 mg if the 10 mg dose proves insufficient, or reduced to megalis 2.5 mg for daily use.

For patients with mild to moderate erectile dysfunction who anticipate frequent sexual activity (twice weekly or more), a daily regimen of megalis 2.5 mg or 5 mg may be recommended.

The maximum recommended frequency is once daily, and the maximum recommended dose is 20 mg per 24-hour period. It’s crucial to adhere to prescribed dosing schedules and never double dose to make up for a missed one. For elderly patients (?65 years) and those with renal impairment, dosage adjustments may be necessary.

How To Take Megalis

It is recommended to take Megalis approximately 30-60 minutes before sexual activity, with or without food, as meals generally have minimal impact on its absorption rate and effectiveness. Extremely high-fat meals may slightly delay absorption. Grapefruit juice and grapefruit products should be avoided, as they can increase blood levels of the medication by interfering with the enzymes that metabolize it, potentially leads to increased side effects.

Alcohol consumption should be limited when taking megalis vs viagra or other medications in this class, as drinking can lower blood pressure and increase the chances of side effects like dizziness, headaches, or increased heart rate.

Megalis Side Effects

  • Headache
  • Dyspepsia or indigestion
  • Back pain and myalgia (muscle pain)
  • Nasal congestion
  • Facial flushing
  • Dizziness
  • Visual disturbances including color tinge or blurred vision

Serious side effects requiring immediate medical attention include:

  • Priapism (painful erection lasting longer than 4 hours)
  • Sudden decrease or loss of hearing, sometimes accompanied by tinnitus and dizziness
  • Sudden decrease or loss of vision in one or both eyes
  • Chest pain, especially if it occurs during sexual activity
  • Severe drop in blood pressure causing lightheadedness or fainting
  • Cardiovascular events including heart attack, stroke, or irregular heartbeat (arrhythmia)
  • Severe skin reactions such as Stevens-Johnson syndrome or exfoliative dermatitis (extremely rare)

Megalis Contraindications

  • Medications containing nitrates (commonly prescribed for angina or chest pain)
  • Recreational drugs called “poppers” such as amyl nitrite or butyl nitrite
  • Alpha-blockers for hypertension or prostate problems (without proper medical management)
  • Severe cardiac conditions including recent heart attack (within 90 days)
  • Severe heart failure or uncontrolled arrhythmias
  • Stroke (within the last 6 months)
  • Uncontrolled hypertension (blood pressure >170/100 mmHg) or hypotension (blood pressure <90/50 mmHg)
  • Non-arteritic anterior ischemic optic neuropathy (NAION) or have history of vision loss due to this condition
  • Severe hepatic impairment (Child-Pugh Class C)
  • Hereditary degenerative retinal disorders, including retinitis pigmentosa

Generic Tadalafil

Tadalis SX

Manufactured by Ajanta Pharma in India, Tadalis SX contains 20mg of tadalafil, identical to megalis 20.

Tadarise

Produced by Sunrise Pharmaceuticals in India, Tadarise offers various tadalafil strengths including 2.5mg, 5mg, 10mg, and 20mg formulations.

Megalis Online

Purchasing megalis 20 mg tablet online is easy. Delivery timeframes for international orders may take 8-14 days depending on customs procedures and shipping methods. Online pharmacies offer discreet packaging without external indications of contents, respecting patient privacy while complying with shipping regulations.

Clomid

 

What is Clomid?

analogue-of-estrogenClomid (clomiphene citrate, or clomiphene), is a structural analogue of estrogens, and inhibits their action by preferentially binding to the receptor of the hypothalamic neuron normally intended for the reception of estrogen hormones. This makes clomiphene a competitive inhibitor of estrogens at the level of hypothalamic receptors. Clomiphene can be used alone in combination with metformin to induce ovulation in infertile women by follicular insufficiency, corresponding to a failure of estradiol production by the ovarian cortex.

A form of infertility is treated in women (follicular insufficiency): the follicles stimulated will grow until only one of them, the follicle of De Graaf, expels the oocyte in the fallopian tube. It is part of the list of essential medicines of the World Health Organization (list updated in April 2013).

Clomid Uses

Clomid is used in the treatment of anovularia associated with alterations of the luteinic phase or due to oligomenorrhea, secondary amenorrhea and polycystic ovary. By inhibiting the negative feedback of estrogen on the hypothalamus, it will stimulate the production of GnRH (gonadotropin-releasing hormone), increasing the production of FSH in the pituitary gland itself. The production of FSH will result, at the level of the ovary, in the increase of the secretion of sex hormones, which will allow the correct course of folliculogenesis. This control also acts on the ovarian follicle contained in the ovary, which it will stimulate.

How does Clomid work?

The therapeutic efficacy of clomiphene citrate contained in Clomid is associated with its dual activity, both mildly estrogenic and anti-estrogenic.

This particular biological characteristic allows the aforementioned active principle to bind to estrogen receptors present at the hypothalamic and pituitary level with high affinity, inhibiting the negative feedback normally exerted by estrogens.

In this way the GnRH axis – Gonadotropins (FSH and LH) – estrogens, remains active, guaranteeing follicular maturation and subsequent ovulation, thus facilitating the establishment of a pregnancy.

How does Clomid work to get pregnant?

Ovarian stimulation cycles should last 5 days, with the daily intake of one tablet. In the event of ovulatory failure, the same cycle could be repeated 2 more times with higher dosages and under strict medical supervision. Each phase of the therapy, from the definition of the dosage to the end of the cycle, should be supervised by your doctor.

How long does Clomid stay in your system?

The important efficacy of Clomid treatment lies in the advantageous pharmacokinetic properties of clomiphene citrate, which allow the patient to take the tablet orally, and the active principle to be easily absorbed at the intestinal level, and thus distributed in the circulation, to be eliminated afterwards a half-life of about 5 days mainly with feces.

Clomid Side Effects

clomid-treatmentThe appearance of side effects on the visual apparatus, fogginess and opacification, could make the driving of vehicles or the use of machinery dangerous.

Despite the short duration of the treatment can significantly reduce the risk of side effects related to the use of clomiphene citrate, it is possible that therapy with Clomid may be associated with the appearance of:

  • nausea
  • vomiting
  • nervousness
  • fatigue
  • headache
  • visual changes
  • increase in volume of ovaries and ovarian cysts
  • abdominal tension
  • abdominal pain
  • vasomotor disorders
  • increased breast tension with tenderness

Fortunately, the aforementioned symptoms tend to reverse easily once the therapy is suspended.

Clomid Precautions

Before undertaking ovarian stimulation processes with clomiphene citrate, it is appropriate to characterize the reason for anovulation in physio-pathological terms and verify that the causes are compatible with the therapeutic indications provided for Clomid.

For this reason it is essential to supervise a specialist doctor in defining the treatment and throughout the therapeutic process. Moreover, the intake of clomiphene citrate, even if indirectly, could determine a volumetric increase of ovarian and cyst ovaries as well as an ovarian hyperstimulation syndrome, such as to require the rapid suspension of therapy.

Statistical data describe how the incidence of twin pregnancies is more frequent in women undergoing ovarian stimulation.

At the moment, given also the short periods of treatment, active ingredients are not known, whose intake, together with that of clomiphene citrate, could determine the onset of clinically relevant interactions.

Clomid Contraindications

The use of Clomid is contraindicated in women with menometrorrhagia, changes in liver function, pregnancy and lactation or in case of hypersensitivity to the active substance or one of its excipients.

Clomid contains lactose therefore it is contraindicated in patients with galactose intolerance, lactase enzyme deficiency or glucose-galactose malabsorption.

The scientific literature reports numerous studies carried out on experimental animal models, in which the intake of clomiphene citrate has contributed to the appearance in the fetus of evident malformations, concentrated above all on the genital, gastrointestinal and nervous apparatus, such as to compromise the survival of the fetus. It is also useful to remember how the intake of this active ingredient during lactation could inhibit milk production.

Clomid Generic Name

  • Clominova – Pharma Synth Formulations Ltd.
  • Clomiriv – EAST AFRICAN(INDIA) REMEDIES PVT.LTD
  • Clomitrop – Modi Mundipharma Ltd.
  • Clopreg – Kee Pharma Ltd.
  • Fertomid – Cipla Limited
  • Ferton Inga Laboratories Pvt. Ltd
  • Fertilin Ind-Swift Limited
  • Fertitone Western Remedies (India)
  • Fertyl Ar-Ex Laboratories Pvt. Lltd.
  • Fission – Biocin Genetics & Pharma
  • Fulfyn – Micro Labs Ltd (India)
  • Infotyl – Shreeyam Health Care
  • Ovipreg – Win Medicare Limited
  • Ovuclom – VHB Lifesciences Inc. (Cronus)
  • Rejun – Uni Sankyo Ltd.

Clomid Online

ordering-ClomidBefore you proceed to look for opportunities to buy Clomid over the counter, you should be informed that this is a prescription drug. It is essential that you seek medical advice before you initiate the therapy with clomiphene citrate.

Clomid generics, as well as the original drug, can be ordered online for a fraction for the price established for the same preparation in the pharmacies of your city. This can be explained by a large number of marketing reasons. By ordering Clomid from an online pharmacy, you agree to terms and policies of its use, so you should familiarize yourself with them in advance. Look for a pharmacy whose policies pursue customer interests first and foremost; there should also be medical services provided if they do not require prescription to be presented when ordering legend drugs, to which Clomid belongs.

Addyi

 

What is Addyi?

womens-sexual-desireAddyi pill, a commercial name for filibanserin, a drug approved by the Food and Drug Administration in 2015, acts on the hypoactive disorder of women’s sexual desire.

10% of women suffer from it and manifest themselves with the persistent or recurrent absence of fantasies and receptiveness with respect to sexual activity. The causes can be age, use of certain drugs, emotional conditions (depression, anxiety and stress) or relationships (conflicts, anger, lack of trust). But above all the imbalance between dopamine, norepinephrine and serotonin, neuro-chemicals involved in the mechanisms underlying female desire.

What is Addyi used for?

Addyi 100mg, also known as the “pink pill”, is the product conceived by the German pharmaceutical company Boehringer Ingelheim, useful for stimulating women’s sexual desire. The goal is to solve problems of a hormonal nature that result in lack of libido, in such a way as to give it a more peaceful and satisfying intimate life. This is not a real drug but rather a food supplement and this is why it may sometimes not be effective, given that the decline in desire in the female sex is caused by both physical and psychological problems. Here is everything you need to know about addyi pills.

How does Addyi Work?

In fact flibanserin, discovered in the 1990s, has always been tested as an antidepressant: the molecule acts on the receptors of serotonin, the “happiness” neurotransmitter whose deficiency is involved in mood disorders, and on two other fundamental brain transmitters, dopamine and noradrenaline. The studies were promising, it seemed that he acted faster than the “classic” antidepressants they serve on average a couple of weeks before seeing the effects on the symptoms. But the change in the purpose of the drug occurred during human experimentation: the women involved often reported an unexpected “side effect”, or a substantial increase in sexual desire. Thus, in the 2000s, a study was started on pre and post-menopausal women suffering from hypoactive sexual desire disorder. Since then there has been a moderate effectiveness of the drug on volunteers, unlike testosterone in patches or gel rejected by regulatory bodies due to total ineffectiveness.

FDA communiqué states the following: “Addyi tablet (flibanserin) is a 1A receptor agonist of serotonin and receptor antagonist 2A, but the mechanism by which the drug improves sexual desire and related disorders is unknown”.

What Does Addyi Do?

Addyi 100 mg tablet treats libido problems and acts on brain receptors, aiming to increase sexual desire. For women, the path is much more complex than for men. Flibanserin combats those “hypoactive sexual desire” disorders, a lack of desire in a more or less long period that can cause stress, problems interpersonal and in some cases depression.

The Addyi pink pill must in fact be taken regularly, every night and not before the sexual act, preferably just before going to sleep, and it starts giving its effects after 6-8 weeks.

Why can’t postmenopausal women take Addyi?

According to pre-production clinical trials, the use of Addyi in postmenopausal women is safe and effective. However, the advisability of flibanserin therapy in this subcategory of patients is not backed by any adequate benefit to risks ratio, since the hypoactive sexual desire disorders (HSDD) in postmenopausal women are explained by hormonal disruptions and other natural factors, for which there exist successful therapies with better studied effects and fewer adverse events. Talk to your doctor if you would like to receive Addyi in postmenopausal age; it is a subject to individual prescription.

Addyi vs Viagra

Addyi-flibanserinUnlike sildenafil used in Viagra, which acts on erectile dysfunction complicating men’s plans, Addyi comes into play in the central nervous system, acting directly on neurotransmitters: it stimulates the release of dopamine, linked to the mechanisms of pleasure and contentment and of noradrenaline, released when we respond to external stimuli. Viagra, on the other hand, is a drug used to treat erectile dysfunction that follows a simple mechanism for a simple physical problem: it sends more blood to the penis to keep it erect and presupposes that sexual desire is present.

The different way of treating the drop in female libido is also reflected in the differences in the dosage between Viagra and flibanserin.

Addyi Precautions

There are certain side effects to Addyi that have fueled the debate on flibanserin in recent years. The drug can cause hypotension and loss of consciousness. The risk increases significantly when there is interaction with alcohol, whose intake during treatment is strongly contraindicated.

Addyi and Alcohol

Simultaneous use of alcohol and flibanserin can lead to sudden and severe drop in blood pressure. It is forbidden to drink alcohol or ingest other drugs. Only in this way can you take the pink pill without risk. The conditional is a must because the US Food and Drug Administration has approved the product after a very long approval procedure interrupted twice because of the risks related to the presence of different side effects. In fact, the drug can cause hypotension and loss of consciousness, a risk that increases significantly when there is interaction with alcohol, whose intake during treatment is therefore contraindicated.

Addyi Cost

how-to-get-flibanserinAddyi is available both in local pharmacies and online, with a significant difference in the addyi price. Traditionally, products in e-tailing stores cost much less, thanks to the model of direct sales, fewer staff members employed, the absence of necessity to rent vending areas and stock rooms, and a number of similar expenditures that get obliterated when it comes down to a transition from bricks to clicks. Although one can safely buy Addyi tablets online at a discount price, it is nevertheless very important that you seek doctor’s advice before you consider to buy  flibanserin on the Internet.

Remember that Addyi is a prescription drug with a number of contraindications that should be considered. Alternatively, you can use the services of a drugstore that offers consultations online with the cost of addyi doctor’s attending already included in the price of the drug you will order; although this service slightly increases addyi 100 mg tablet price, it provides an additional layer of safety – and the price for flibanserin ordered in this way still remains much lower comparatively to its brand analogs sold in the drugstores of your city.

Lady Era

What is Lady Era?

Lady Era tablet (sildenafil citrate) is an oral drug used in women with manifested disorders related to the sexual desire and the ability to derive satisfaction from their sexual experiences. When you look up Lady Era tablet Wikipedia entry will refer you to sildenafil citrate page, which is the same ingredient as is featured in Viagra used in men with erectile issues and Revatio used in both men and women with PAH (pulmonary arterial hypertension). How come? If we consider the Lady Era composition, we will discover that the drug has sildenafil citrate as its active component. It works by improving blood circulation in the body, addressing physiological barriers to intimacy, and promoting overall sexual wellness. Hence, you guessed it, Lady-Era Female Viagra moniker that is so widespread among consumers. While not the most scientifically accurate, this nickname catches the gist of sildenafil citrate Lady Era edition, as it ultimately serves the same purpose: bringing back the ability to enjoy physical intimacy.

What is Lady-Era as a drug type? Lady Era belongs to the class of PDE5 inhibitors. Those are vasoactive substances, meaning they improve the blood flow by making the walls of blood vessels more elastic. This product has become a well-known option among individuals seeking non-invasive solutions for enhancing libido and overcoming challenges such as decreased sexual interest or arousal difficulties.

female-viagra-review

PDE5i’s work by blocking the enzyme phosphodiesterase which normally reduces the levels of a substance called cyclic GMP (cGMP). By blocking the degradation of cGMP, drugs from this class keep the sexual function more solid and longer, but sexual stimulation is still required to produce an erection in males and clitoral erection in females; the daily formulation is used in women to ensure the coverage of the drug constantly, rather than as needed.

The attempt at world level is to use these drugs for preventive purposes, and in this case, we also try to verify the effect on the circulation and on the female genital tissues: the goal of taking Lady Era 100mg is to be able to envisage longer and more satisfying sexual health and a better quality of life.

So, what is behind the package of Lady Era? This is a common question for those curious about female enhancement solutions. Lady Era is a medication designed specifically for women. The drug offers support for enhancing sexual desire and addressing issues related to female sexual dysfunction. It has gained popularity for its ability to improve sexual satisfaction and help restore balance in intimate relationships.

The pill itself goes by many names other than its official name: you will see search engine requests spelling the drug’s name as a closed compound Ladyera, Lady.Era, or the hyphenated Lady-Era, while others might misspell and look for the pill by Leidy Era or Ledy Era, not to mention sloppy typos like Lady Erg or Lady Rra. All of this just shows the popularity of the pill; a beloved child has many names.

But what is Lady Era capsule? The denomination is not official and misleading, since the drug has no capsule form, strictly speaking, but comes in a form of film-coated tablet. It is still an oral medication containing sildenafil citrate as its active ingredient. This compound is commonly associated with improving blood flow and addressing physical factors related to sexual stimulation. The tablet form makes it convenient to use, ensuring an easy and straightforward method of administration just as capsule would be.

The lady era pill is another commonly searched phrase, reflecting its popular usage. This pill is known for its unique formulation, designed to provide quick results when taken before planned intimacy. Its role in reducing stress and creating a conducive environment for intimacy has made it a preferred choice for many women. It is a reliable choice for addressing female sexual wellness. It stands out as a product designed with care and precision to meet specific needs that have often been overlooked in traditional healthcare options.

Lady Era uses

Understanding what is Lady Era medicine used for can help set realistic expectations for its benefits. Lady Era is designed to address sexual dysfunction in women by improving blood flow and enhancing physical responsiveness during intimacy. Its effectiveness lies in its active ingredient, sildenafil citrate, which has been shown to support increased sensitivity and satisfaction.

When it comes to Lady-Era tablet uses, the primary focus is on helping women experiencing reduced libido or difficulty achieving sexual satisfaction. It is particularly useful in overcoming physical barriers like insufficient blood flow to the genital area, which can impact arousal and overall sexual experience.

For those curious about Lady Era tablet 1mg uses, it’s worth noting that the medication typically comes in a 100mg dose, but lower doses may be prescribed depending on individual needs. A reduced dose is often used for those who are more sensitive to medication or need a smaller amount to achieve desired results.

If you’re wondering how to use Lady Era, the instructions are straightforward. Take the tablet orally with water, ideally 30 to 60 minutes before intimacy. For optimal results, avoid consuming heavy meals or alcohol beforehand, as these can delay absorption and reduce effectiveness.

Ultimately, what is Lady Era medicine used for comes down to enhancing sexual wellness and addressing physiological barriers to intimacy. With proper use and guidance from a healthcare provider, it can be a safe and effective solution for improving the quality of intimate experiences.

How to take Lady Era

The response window of sildenafil used as the active substance in Lady Era pill is estimated at 60 minutes, but in the majority of patients, the effects can be felt already 40 minutes after the intake. Taking the drug on an empty stomach speeds up the onset of health benefits. Continued use of lady-era tablet also decreases the response time.

Lady Era, otherwise referred to as Female Viagra, works best when taken before sexual activity. Taken daily, sildenafil exerts an accumulative effect that becomes more significant with every consecutively taken tablet. Thus, when a tablet of Lady Era 100mg is taken on a day when sexual activity is planned, its health outcomes are maximal. Take lady era pills 40-60 minutes before the expected activity. Wash the pill down with a sufficient amount of water; avoid taking grapefruit or pomelo fruits or juice when taking sildenafil.

Lady Era uses are not limited to sexual enhancement. Multiple studies have shown the efficacy of the drug in improving the quality of sexual life in women with diabetes and a healthy female population. In women with type 1 diabetes, it is possible to find an increase in sexual dysfunction, mainly due to the effects that the disease has on peripheral vascular circulation. A trial conducted by Caruso and collaborators of the University of Catania sought to determine whether the daily intake of PDE5 inhibitors is effective in pre-menopausal diabetic women suffering from genital arousal disorder. Thirty-three volunteers were given this drug for 12 weeks.

The aim was to evaluate the effectiveness of daily PDE5i use on sexual genital excitation, desire, orgasm, pleasure, and frequency of sexual activity, and also on the presence or absence of genital pain; these variations were subjectively assessed through a questionnaire and objectively through an echo-color-doppler of the blood flow in the clitoris. Furthermore, the improvement of the quality of life was evaluated. The thirty-two women who completed the course report an improvement in the quality of life at week 12. Using the drug would seem to improve the experience of genital sexual arousal and orgasm, sexual pleasure, satisfaction, and frequency of sexual activity and fantasies. Finally, there has been a reduction in dyspareunia.

Lady Era effects

In women with decreased sexual desire, difficulty reaching orgasm, or complete anorgasmic states, Lady Era – female Viagra is the first-line defense against the dysfunctional patterns in sexual responses. Taken regularly, the drug can help eliminate the issues in the long run; but even when taken occasionally, Lady Era Viagra can:

  • decrease stress and anxiety
  • create the right mood for sexual activity
  • promote sexual desire
  • increase blood circulation in the genitals
  • help overcome the problem of vaginal dryness
  • fight dyspareunia symptoms
  • boost libido in post-menopausal syndrome
  • facilitate orgasm achievement
  • promote general satisfaction with sexual experiences

Sildenafil contained in Viagra and Lady Era medicine stimulates sexual desire, as it acts directly in the nervous system of the genitals. It promotes blood circulation, increases blood pressure, and facilitates blood circulation. As a result, you feel fit and secure in bed. The relaxing effect of Lady Era 100mg tablet also has a positive effect on sexual life.

Using the synergistic action of its active ingredients, Lady-Era pill stimulates the receptors destined to awaken the libido, helping a woman let go, enjoy multiple orgasms, and forget the anxiety usually felt during intimate activity.

The decline in female sexual desire is caused by the combination of mental and physical factors, and in the event that the so-called “pink pill” fails to solve the problem, it is necessary to change one’s couple habits, perhaps following psychological therapy with the partner or by identifying the pathology that causes the disappearance of libido. In all cases, it would be good to talk to your doctor to shed light on the problem.

The Lady Era sildenafil citrate formula is specifically made to help improve blood flow and enhance responsiveness during intimacy. It works best when taken as directed, giving the support you need when it matters most. Checking out an average Lady Era pill review, you’ll often see users sharing positive experiences about how easy it is to use and how effective it can be. Many mention feeling more comfortable and satisfied, especially when taking it ahead of planned intimate moments.

Lady Era side effects

effectiveness-of-Lady-EraLady Viagra is reported to cause the following side effects:

  • headache
  • stomach upset
  • nasopharyngitis
  • facial flushing
  • nausea
  • skin rash
  • changes in color perception
  • muscle aches
  • ringing in the ears

This list is not complete. The side effects of Lady Era capsule mentioned above are usually fleeting and disappear with the continued use of the drug; if they persist or aggravate, consult your doctor; an adjustment of the dose can be required. Note that taking Lady Era tablet side effects alongside meals can decrease the manifestation and intensity of sildenafil side effects.

Seek medical help immediately if you experience one of the following severe Lady Era tablets side effects:

  • pain in the chest or arm
  • swelling of the face, lips
  • irregular heartbeat
  • loss of vision
  • severe allergic reactions
  • fainting

Note that Lady Era dosage directly affects the incidence of side effects. This means that higher doses come with higher risk of developing side effects, and the opposite is also true. For those who find Lady Era side effects too bothersome or persistent, doctors recommend halving the dose. Lady Era pill side effects are most likely to become significantly milder even if they do not disappear altogether.

Higher doses of sildenafil, such as Lady Era for women 100mg, are more likely to cause side effects. While the 100mg dose is often prescribed for its strong efficacy, it may not be the best fit for everyone, especially for women who are new to sildenafil or have specific sensitivities. While these side effects are typically temporary, they can be uncomfortable and may deter consistent use.

If you experience side effects with your current dose, it’s worth discussing with your doctor whether a lower dose, such as 50mg or even 25mg, might be a better option. Lower doses often deliver noticeable benefits while reducing the likelihood of side effects. For example, a woman struggling with mild side effects at 100mg may find 50mg equally effective for improving sexual response without the discomfort.

Follow these tips for managing side effects:

  • Take with sufficient amount of water and after a light meal, not on an empty stomach, this will help mitigate gastrointestinal adversity.
  • Avoid alcohol and grapefruit, since both can increase the risk of side effects by interfering with the way the medication is processed in your body.
  • Start small: if you’re new to lady era, consider starting with a lower dose to gauge your body’s response before increasing to 100mg.

The 100mg dose of Lady Era is designed for maximum effect, but every individual’s tolerance varies. Open communication with your healthcare provider is key to finding the right balance between dose and comfort, ensuring you get the benefits without unnecessary discomfort. By adjusting your approach, you can achieve satisfying results while minimizing side effects.

Lady Era safety of use

Is Lady Era safe? This is a very legitimate concern everyone should have before starting on a new drug. Since sildenafil citrate was first introduced in 1998, countless studies have been conducted to evaluate its safety and effectiveness – not just for men but for women as well. These studies have consistently shown that, when used under proper medical supervision, sildenafil is generally well-tolerated.

For women, trials have focused on how sildenafil citrate, the active ingredient in Lady Era, improves blood flow and its potential benefits for sexual wellness. The results have been promising, with most participants experiencing minimal and manageable side effects. Commonly reported issues like mild headaches or flushing tend to fade as the body adjusts to the medication.

Over the decades, the safety profile of sildenafil has been extensively reviewed, making it one of the most researched drugs of its kind. However, as with any medication, its use must be personalized. That’s why consulting a healthcare provider is so important – they’ll ensure that it’s the right option for you based on your medical history and current health.

Lady Era sildenafil citrate tablets are safe to use only provided you have consulted a healthcare specialist and they confirmed that sildenafil citrate can be used without complications in your individual case. This precaution is especially important for individuals with cardiovascular conditions, as sildenafil citrate affects blood flow and circulation. Neglecting to consult a specialist could lead to unexpected complications, so it’s always better to err on the side of caution.

Watch out for any eventual Lady Era tablet side effects that were mentioned above; if they are persistent, intense or go beyond the common, seek medical help without delay.

Lady Era vs. Female Viagra: which is best?

When comparing Lady Era for women 100mg to Female Viagra, the answer is simpler than it seems: they’re essentially the same. Both medications use sildenafil citrate as their active ingredient, designed to improve blood flow and enhance sexual responsiveness. The primary difference lies in branding and packaging, not in the actual formulation or effectiveness.

Both Lady Pills and Female Viagra (or Female Era, as it is sometimes referred to) contain the same active ingredient, sildenafil citrate. And just like in case of Lady Era Female Viagra 100mg of sildenafil is a standard dose. This dose is considered effective for addressing issues related to sexual dysfunction by increasing blood flow to the genital area. The dosage remains identical, making the two medications comparable in their intended results and pharmacological function.

When it comes to mode of intake, both are oral medications designed to be swallowed with water. They work best when taken on an empty stomach, approximately 30-60 minutes before planned intimacy. This allows the active ingredient enough time to be absorbed into the bloodstream, ensuring optimal results. The onset time for both medications is similar, with effects typically felt within 30 to 60 minutes after consumption, depending on individual response and external factors like food intake.

The effects of both medications focus on enhancing physical responsiveness, increasing lubrication, and improving overall satisfaction during intimacy. However, they do not work without sexual stimulation and should not be mistaken as aphrodisiacs. Both can also cause mild to moderate side effects such as headaches, flushing, nasal congestion, or dizziness, which are usually short-lived. More rarely, gastrointestinal discomfort or changes in vision may occur. It’s essential to consult a healthcare provider if any side effects persist or worsen.

Contraindications are the same for both Lady Era and Female Viagra. These medications are not recommended for individuals with certain cardiovascular conditions, low blood pressure, or those taking nitrates. Consulting a healthcare provider before use is critical to ensure safety, especially if you have pre-existing medical conditions or are on other medications.

Ultimately, the choice between Era Lady and Female Viagra should focus not on their minimal differences but on the reliability of the manufacturer and retailer providing the product. By prioritizing verified sources, you can ensure the medication’s quality and safety regardless of its branding.

What truly matters, as discussed above, is not choosing between these two names but ensuring that you purchase from a reputable manufacturer and trusted retailer. Whether it’s marketed as Lady Era 100mg or Female Viagra, the quality and safety of the medication depend entirely on the producer and distributor adhering to high standards. Counterfeit or subpar products from unverified sources can undermine the effectiveness and safety of these medications, regardless of their label.

In the end, instead of focusing on the brand name, focus on finding a verified source with a strong reputation. The effectiveness of the medication will always rely more on the credibility of the manufacturer and retailer than on the name printed on the box.

Lady Era in the U.S.

When it comes to Lady Era USA is one of those countries where it is challenging – but not impossible – to find the medication. While it cannot be found locally and you will not find much if you try looking for Lady Era pills near me, Female Viagra Lady Era is still available online.

As a solution frequently searched for by women Viagra Amazon beats search queries like Lady-Era pills, but we’ve already covered that: essentially, there is no difference other than the product name. What you should focus on is the authenticity of Lady-Era tablet, and this can be ensured by checking the manufacturer. it’s reassuring to know that several reputable Indian pharmaceutical companies have been approved by the FDA for the production of sildenafil. These manufacturers adhere to strict quality standards to ensure that the product is both safe and effective. Names like Cipla, Sun Pharma, and Aurobindo Pharma are well-known for their compliance with global pharmaceutical regulations and are trusted worldwide.

Purchasing Lady-Era from a manufacturer with FDA approval gives you confidence in the product’s quality. These companies follow rigorous processes, from sourcing high-grade ingredients to ensuring consistent production standards. Always look for clear labeling, proper packaging, and documentation that ties the product back to a verified manufacturer. This ensures you’re getting a genuine tablet that meets the necessary health and safety benchmarks.

Be wary of products with downright suspicious names, the look-alikes like Ldy Era, Ledy Era, Lafy Era or Lady Eara – you get the drift. While users sometimes make legitimate errors entering the name the drug and end up searching for Era Lady or Female Era, with an occasional typo that can slip through the cracks (our top favorites are Ladt Era, Lady Wra, and Lady Ere), search engines will correct your query and refer you to trustworthy pages where user experience, including spell-checks, is on point, and the drug is listed under its official name of Lady Era.

Lady Era online review

When considering the many forms of Lady Era available on the market, it’s important to exercise caution. From pills and drops to soluble tablets and pastillas, the variety of drug forms can be overwhelming. While it’s easy to stumble upon a Lady Era pill review or a Lady Era Drops review that sings praises about these options, relying solely on reviews is not the best approach. What you need to understand is that no Lady Era Reddit reviewer, no matter how well-meaning, will replace a consultation with a specialist. User experiences are subjective and may not guarantee the safety or authenticity of the product.

Take, for example, the Lady Era Soluble review or the highly popularized Lady Era Gold review—these provide insight into customer satisfaction but often lack the crucial context of the product’s origin. Not all forms of Lady Era are manufactured by licensed and reputable companies. This can lead to inconsistencies in quality, which might affect not only the effectiveness of the drug but also its safety.

The Lady Era price may vary widely across these different forms, but cost alone should not dictate your decision. Instead, focus on the reputation of the manufacturer and retailer. Look for verified sellers and licensed producers who adhere to rigorous quality standards. These are the true beacons to guide your choice, ensuring you receive a product that meets safety and efficacy benchmarks. Always prioritize the reliability of the source over anecdotal evidence from reviews.

Where to buy Lady Era

If you’re looking to improve your sexual wellness, it’s important to know how to buy Lady Era online safely and securely. With numerous options available, finding the right source for authentic products can feel overwhelming. However, by focusing on reputable vendors, you can ensure that you’re purchasing genuine medication that meets quality standards.

When searching for Lady Era for sale, prioritize established online pharmacies or platforms with verified customer reviews. These vendors often provide detailed product information, ensuring transparency about ingredients, dosage, and manufacturer details. This is especially crucial for products like the Ladyera pill, where authenticity is key to ensuring both safety and effectiveness.

Online platforms often offer discreet shipping options, competitive pricing, and easy access to customer support. Always double-check that the website is secure and provides contact details or certifications for added peace of mind.

If you live in the U.S.A. and find yourself in need of Lady Viagra buy online by all means, but make sure that you are ordering from a verified retailer. Only buy from platforms that provide clear information about the product’s origin and manufacturer. Look for online pharmacies with proper certifications or seals of approval, such as those accredited by organizations like Verified Internet Pharmacy Practice Sites (VIPPS). This ensures the retailer follows strict safety and quality guidelines.

Customer reviews can also be a valuable resource. Choose vendors with consistently positive feedback about their service, delivery reliability, and product authenticity. Reputable retailers will often offer detailed descriptions of the Lady Era pills they sell, including dosage information and any relevant precautions.

Additionally, ensure that the website uses secure payment methods and displays clear contact information. Avoid vendors with vague descriptions or unreasonably low prices, as these can be red flags for counterfeit products. By sticking to trusted sellers, you’ll not only secure genuine medication but also enjoy the peace of mind that comes with a safe transaction.

By following these steps, buying Lady Era becomes a straightforward process, helping you focus on the benefits the product can provide rather than worrying about its origin.

Lovegra

What Is Lovegra

Lovegra 100mg tablets (sildenafil citrate) contain the same active ingredient found in traditional Viagra but are specifically formulated for women’s sexual health needs. This pink pill aids women with decreased sexual desire or difficulty achieving satisfaction during intimate moments. Lovegra pills increase genital sensitivity, promote natural lubrication, and enhance responsiveness to sexual stimulation.

How Does Lovegra work

Lovegra contains sildenafil citrate, the primary component of PDE5 inhibitor class of medications. Sildenafil functions by inhibiting phosphodiesterase type 5 (PDE5), an enzyme predominantly found in genital tissues. PDE5 inhibition stimulates the release of cyclic guanosine monophosphate, which subsequently triggers increased nitric oxide levels in the bloodstream and leads to potent vasodilatory action. Increased blood circulation proves especially beneficial for women struggling with vaginal dryness. When blood flow increases to the female genital area, Bartholin’s glands receive greater perfusion, leading to enhanced natural lubrication. Additionally, the clitoris becomes more sensitive due to increased blood flow.

Lovegra Dosage

lovegraStandard dosage for lovegra tablets is one 100 mg tablet taken approximately 60 minutes before sexual activity. Lovegra 100 is effective for 4-6 hours after ingestion. First-time users can start with half a tablet 50 mg.

The maximum recommended frequency is one sildenafil lovegra tablet within a 24-hour period. Female viagra lovegra 100mg should never be taken multiple times daily regardless of sexual activity frequency. Never take a double dose to compensate for a missed one. Lovegra tablets works on-demand and isn’t designed for daily regular use.

How To Take Lovegra

Take one tablet with a full glass of water approximately 60 minutes before sexual activity. Lovegra can be taken with or without meals, but be aware that high-fat meals may delay absorption and onset of action. For fastest results, take lovegra on an empty stomach or after a light meal. Avoid grapefruit juice, as this can interact with lovegra and potentially increase side effects. To maximize lovegra  100 mg effect, avoid heavy meals before taking the medication, stay adequately hydrated, and ensure you’re genuinely interested in sexual activity.Alcohol consumption should be limited. Excessive alcohol can diminish the Lovegra effectiveness and increase the likelihood of experiencing side effects like dizziness or headaches.

Lovegra Side Effects

Common adverse reactions include:

  • Headache
  • Facial flushing or warmth
  • Digestive discomfort including indigestion or mild nausea
  • Nasal congestion or runny nose
  • Dizziness or lightheadedness, particularly when standing quickly
  • Temporary vision changes including blue-tinted vision or increased light sensitivity
  • Muscle aches or back pain

Serious side effects that require immediate medical attention include:

  • Severe drop in blood pressure causing extreme dizziness or fainting
  • Chest pain or irregular heartbeat
  • Priapism in the clitoris (prolonged, painful sensitivity lasting over 4 hours)
  • Sudden decrease or loss of vision in one or both eyes
  • Sudden decrease or loss of hearing, sometimes with ringing in the ears
  • Severe skin reactions including rash, itching, or swelling

Women taking medications containing nitrates should never use lovegra with viagra or any sildenafil product as this combination can cause a dangerous drop in blood pressure.

Lovegra Contraindications

  • Medications containing nitrates for chest pain or heart conditions
  • Nitric oxide donors or recreational drugs containing amyl nitrite (“poppers”)
  • Severe cardiovascular disease including recent heart attack, stroke, or life-threatening arrhythmia
  • Severe hepatic impairment or liver disease
  • Severe hypotension (blood pressure below 90/50 mmHg) or uncontrolled hypertension (blood pressure above 170/100 mmHg)
  • Retinitis pigmentosa or other hereditary degenerative retinal disorders
  • Non-arteritic anterior ischemic optic neuropathy (NAION)
  • Pregnant or breastfeeding (limited data on sildenafil safety during pregnancy makes it contraindicated)

Female Viagra Generic Names

Lady Era

Manufactured by Ajanta Pharma in India, Lady Era contains 100mg sildenafil citrate identical to lovegra’s active ingredient.

Womenra

Produced by Centurion Laboratories in India, Womenra delivers 100mg sildenafil citrate per tablet.

Lovegra Online

Sildenafil itself is FDA-approved medication in United States. Many women obtain lovegra through online pharmacies that ship internationally from countries where regulatory frameworks differ. Shipping times typically range from 7-14 days for international orders. For regular users, some online pharmacies offer subscription services with automated refills and discounted pricing.

Nolvadex

 

What is Nolvadex?

Nolvadex 20mg is a selective anti-oestrogenic drug used in the treatment of breast cancer and has recently been re-evaluated for the short-term treatment of anovulatory female infertility.

What is Nolvadex used for?

Estrogens are a naturally occurring substance in the body known as “sex hormones”. Nolvadex 20 mg works by blocking the effects of estrogen on your body. Nolvadex is indicated:

  • in the treatment of breast cancer;
  • in men in the prevention and treatment of breast augmentation (gynecomastia) and breast pain (mastalgia) caused by medicines called antiandrogens and used in the treatment of prostate cancer (prostate cancer), a gland that produces in humans the seminal fluid.

Talk to your doctor if you do not feel better or if you feel worse.

What does Nolvadex do?

Nolvadex_TamoxifenTamoxifen is administered after surgical treatment in pre and post-menopausal patients to reduce the risk of relapse. Tamoxifen is usually administered after the conclusion of chemotherapy. Tamoxifen is often administered before surgery to reduce the size of the tumor so that excision can be limited to the nodule rather than extended to the whole breast (mastectomy).

Tamoxifen is sometimes used to keep the disease under control, often for long periods of time, and also to reduce the size of a tumor that has recurred after treatment or that cannot be removed because it is too large at the time of the first diagnosis.

Nolvadex Dosage

Nolvadex is administered in the correct dose to patients for daily intake, with the regular doses ranging between tamoxifen 20 mg and 40mg daily. One tablet of Nolvadex contains 10mg or 20mg of the active substance. The dose is appointed by the supervising healthcare practitioner. The required dose can be split between two intakes or taken as a single dose. Dose adjustment is not required in the geriartrics.

Tamoxifen is given by mouth. The dose is preferably taken at the same time. Since tamoxifen can cause nausea and leave a metallic taste in the mouth, some patients prefer to take it when during meals.

Nolvadex vs Clomid

Both Nolvadex and Clomid are a serum to use in eg PCT. Some people react a little differently to them. Nolvadex is considered to be a little more effective and give lesser side effects in general.

In men, Clomid can be used both as an antiestrogen, and a gonadotropic stimulant (which stimulates the glands). Male steroid users find it helpful to prevent gynecomastia when using steroids. It also helps to restore your own testosterone production to the normal, after completed steroid cycle, Clomid acts directly on the pituitary gland that is stimulated to increase the production of gonadotropic hormones. No adverse effects have been observed in those who have used this drug. It can be quite effective, but not more effective than HCG or Novaldex in this area. The most common dose during short courses is 50 mg per day.

Nolvadex vs Arimidex

The two medications, Nolvadex and Arimidex, are applied with the same purpose of anti-estrogen agents. The mechanism of action is different for Nolvadex and Arimidex, while their medicational purposes are the same. Arimidex lowers the estrogen levels in the body, while Nolvadex blocks certain receptors (does not lower estrogen).

In bodybuilding, Nolvadex usually gives less side effects, but it is individual. However, in some cases it is better to use Arimidex during the course to avoid the gynecomastia phenomenon and restrict Nolvadex use for PCT.

In addition, it is good to continue with the Arimidex about 3 weeks after the end of the course (after starting with Clomid) as it also increases the body’s own testosterone production. Along with virtually zero aromatization it contribues to complete recovery.

Nolvadex vs Proviron

In comparison to Nolvadex, Proviron is reported to have fewer and milder side effects. Nolva or Proviron counteract both estrogen conversion in different ways.

Proviron is a low androgenic steroid that promotes lean muscle mass gains and protects against gynecomastia taken in the doses between 50mg and 100mg. Proviron is usually taken as a part of PCT in subjetcs with poor response to Nolvadex in order to increase testosterone production and augment sex drive. However, Nolvadex is generally considered to be better than Proviron against water retention.

Nolvadex and PCT

Both Nolvadex and Clomid are a serum to use in eg PCT. Different people react a little differently to them. Nolvadex for men is considered to be a little more effective and give fewer side effects in general.

Nolvadex is an effective antiestrogen, not a steroid. It is used against estrogen dependent tumors, e.g. breast cancer. Steroid users take Nolvadex to prevent the effects of estrogen in the body. This estrogen is usually a result of aromatizing steroids. Nolvadex can help prevent edema, gynecomastia and female fat distribution, all of which can occur when a man has a high estrogen level. These effects can also occur at too low androgen levels, as estrogen becomes the dominant hormone. This can happen when the endogenous androgens are suppressed as a result of prolonged use of exogenous steroids.

Nolvadex works by binding to receptors in the target estrogen region, e.g. in the breasts, so that it competes with the estrogen. This drug is not toxic, and some side effects have not been observed in athletes who used it as an antiestrogen. This is the most popular antiestrogen among steroid users. Although it does not appear to be 100% effective in everyone, it seems to have a certain effect for most people. In some bodybuilders it seems so good that they can take medicines like Anadrol right before a competition, as long as they combine these with Nolvadex.

Nolvadex Side Effects

Tamoxifen-side-effectsLong-term therapy, necessary for the treatment of breast cancer, exposes the patient to numerous side effects linked to the use of tamoxifen.

More precisely, hot flashes, vaginal blood loss, skin rash, dermatitis, hydro-saline retention, dizziness, visual disturbances, lower limb cramps, volumetric increase in ovarian cysts, hepatic steatosis and liver failure are the most frequently observed adverse reactions in progress of therapy with Nolvadex.

However, those that are of most concern, assuming particular importance from the clinical point of view, are linked to the greater incidence of developing embolic thrombus events and malignant pathologies concentrated mainly in the uterine and endometrial area.

Nolvadex Precautions

Nolvadex should be administered with caution in patients with a decrease in the number of blood cells (leukopenia) and with a decrease in the number of platelets (thrombocytopenia). Therefore, regular blood tests should be performed. Tamoxifen can cause cataracts, so eye checks must be performed.

As Nolvadex can cause alterations – even serious – of the uterus, regular gynecological checks should be performed.

Nolvadex Contraindications

The use of Nolvadex is contraindicated in the following cases:

  • Known hypersensitivity to tamoxifen;
  • As a preventive therapy in patients at high risk of developing breast cancer;
  • In patients with ductal carcinoma in situ (an initial form of breast cancer, also called precancerous);
  • In patients who require concurrent anticoagulant therapy;
  • In patients with a history of deep vein thrombosis;
  • In patients with a history of pulmonary embolism;
  • In children and adolescents;
  • Pregnancy;
  • During breastfeeding.

Nolvadex For Sale

Nolvadex can be ordered online, which is a better way to save money on pharmacy shopping, and a more hassle-free routine as compared to getting the medication at an actual pharmacy store. A healthcare specialist can consult you as for the right use of the medication if you choose an e-drugstore with an in-house practitioner, and your Nolvadex pills will be delivered to you in average within 10 work days, anonymously and safely.

Xenical

 

What Is Xenical?

Active Substance & Action Mechanism

Xenical drug contains as active substance orlistat. Approved indication is the treatment of obesity (BMI> 30 or BMI> 28 and other risk factors). The effect is exerted locally by inhibiting the lipases in the intestine, thereby reducing the degradation of triglycerides and decreasing the absorption of fat. In extensive clinical studies it has been shown that the difference in response rate (weight loss> 10% of body weight) between placebo treatment and orlistat treatment is 12% after one year of treatment. Average weight loss after one year of treatment compared to placebo was 3.2 kg. Stool disorders occur in about 20% of patients during the first year of treatment and about 4% during the second. Treatment with orlistat should not be given for more than two years before further data are available.

Xenical Orlistat is optically active. The choice of synthetic pathway ensures that only one of 16 possible isomers is formed. Furthermore, two different crystal structures of the substance are possible, but only one (the thermodynamically most stable) modification is used in the preparation.

Xenical Dosage

weight-lossWhile individual administration pattern for Xenical may differ from patient to patient and is subject to doctor instructions, the general orlistat dosage instructions go along the lines of taking a 120mg capsule with meals, 3 times a day, spacing them out evenly. To get the best results with the treatment, you should avoid high-fat snacks between meals such as cookies, candy bars, etc.

Xenical only works in the presence of food containing fat. Therefore, you do not need to take Xenical if you missed a meal or if you eat a meal that does not contain any fat.

Tell your doctor if for some reason you have not taken your medication that you have been asked to do. Your doctor may otherwise believe that the drug has not been effective or that you cannot tolerate it and may therefore change your treatment unnecessarily.

Xenical instructions

Xenical 120mg capsules is indicated for the treatment of obese patients with a body mass index (BMI) greater than or equal to 30 kg / m2 or overweight patients (BMI> 28 kg / m2) with concomitant risk factors in combination with a moderately calorie reduced diet.

Treatment with orlistat 120mg capsules should only be initiated if only diet has previously given a weight loss of at least 2.5 kg over a period of 4 consecutive weeks. Treatment with xenical orlistat 120mg should be discontinued after 12 weeks if patients have failed to lose at least 5% of the body weight measured prior to initiating therapy.

Xenical In Weight Loss & Weight Control

generic-xenicalFor the treatment of obesity, there have previously been several drugs approved by FDA. Common to these was that they exert their effect in the central nervous system by suppressing appetite. They were deregistered, among other things, because they were central stimulants and often led to abuse. Now a new anti-obesity drug has been approved, orlistat. This agent exerts its effect by inhibiting the lipases in the intestine, thereby reducing the degradation of triglycerides and causing fat malabsorption. The effect is dose-dependent with approximately 23% inhibition of fat absorption at the dose of 120 mg x 3. In clinical trials, fat secretion in the stool was approximately 3 g per 24 hours at the start of treatment and 23 g per 24 hours after one year of treatment with orlistat 120 mg x 3.

The effect of orlistat has been studied in four dose titration studies involving 1,421 patients treated at doses of 10-240 mg x 3 for 2-6 months.

The documentation included seven long-term studies with a placebo run-in period of 1-6 months, after which the patients were treated with placebo or orlistat 30-120 mg x 3. A total of 4,188 patients were treated for 1-2 years. These phase III studies were double-blind and randomized parallel group studies. Apart from a study where the run-in period was six months, the studies were conducted according to the same protocol.

The primary measure of effectiveness was body weight change (weight loss after one year of treatment and prevention of weight gain after two years of treatment). Secondary efficacy measures were related to risk factors in obesity: cholesterol, LDL, HDL, VLDL cholesterol and triglycerides, lipoprotein A, apolipoprotein A1 and B, blood pressure, insulin and glucose and anthropometric measures such as waist size and quality of life.

Xenical vs. Orlistat

Orlistat, the active substance used in Xenical and making it what it is, is available in its generic form. It is commonly known that when the patent for exclusive manufacturing rights owned by the developer of the drug production expires and other pharmaceutical companies can pick up production, the drug price drops. One of the most commonly alluded to disadvantages of Xenical happens to be exactly that: its prohibitive cost. Logically then, with none of the high cost entailed, generic Xenical (Orlistat) easily becomes a next to perfect solution for weight loss.

Generic version of the drug is produced according to the same high manufacturing standards imposed by authorities in healthcare and pharmacology internationally. The composition, mechanism of action, method of administration and safety are identical for both brand and generic drug forms. The only differences are, understandably, the name – generic Xenical is produced under its generic name Orlistat, and some excipients. Excipients are auxiliary substances used to give the drug its form and color. Let’s compare the excipients in generic and brand Xenical:

Generic Orlistat

Capsule content: Microcrystalline cellulose, sodium starch glycolate (type A), colloidal anhydrous silica, sodium lauryl sulfate.

Capsule shell: gelatin, titanium dioxide (E171), indigo carmine (E132).

Brand Xenical

Microcrystalline cellulose (E460), sodium starch glycolate (type A), povidone (E1201), sodium lauril sulfate and talc. The capsule shell includes gelatin, indigo carmine (E132), titanium dioxide (E171) and ink.

Xenical Side Effects

Possible undesirable effects related to the pharmacological effect studied were: decreased systemic absorption of lipophilic substances, eg fat-soluble vitamins, alteration of calcium and bone metabolism, increased fecal fat secretion, and laboratory tests on organ function.

The main side effects of the gastrointestinal drug are: steatorrhea, that is to say, fatty and loose stools, because orlistat blocks the absorption of some of the dietary fat.

  • Fecal incontinence;
  • Uncontrollable diarrhea: frequent or urgent stools;
  • Flatulence and associated colics;
  • In individuals with type 2 diabetes, drop in blood sugar levels;
  • Some patients may develop high levels of oxalates in the urine;

Orlistat can cause liver damage. Serious hepatitis, however, remains exceptional and it is possible that these accidents are related to factors other than the use of this drug.

The main adverse effects of Xenical are related to the presence of lipids in the diet. Pharmacists trained to this prescription by laboratories advice, therefore, to reduce fat in the diet during treatment, which in itself is a diet that allows a weight reduction.

According to Roche, xenical 120 side effects are more severe at the beginning of therapy and decrease over time16. This approach is supported by the results of the XENDOS study, which found that only 36% of people have undesirable gastrointestinal effects in their fourth year of Xenicnal use, while 91% of people with the study had at least one undesirable gastrointestinal effect during the first year of treatment. This reduction in side effects could be associated with a change in a diet lowering fatty foods.

Zyban

 

What is Zyban?

nicotine-abstinence-syndromeZyban tablets (bupropion) is an oral medication that reduces the severity of anxiety states. Its use is justified when anxiety becomes unbearable and lasts over time. Unlike other anxiolytic drugs it does not promote sleep.

Bupropion (also known as amfebutanone) is an atypical antidepressant whose structure closely resembles that of amphetamine, a powerful stimulant of the central nervous system. However – despite the similarity with amphetamine – bupropion has a completely different pharmacological activity.

Zyban 150 mg is available for oral administration as tablets. As the drug can cause sleep disturbances, taking the tablets before bedtime is not recommended.

Zyban is a drug that is not only used for the treatment of major depression, but is also used in smoking cessation therapy. In fact, in addition to inhibiting dopamine reuptake (a mechanism responsible for the antidepressant action), the drug also has an antagonistic action against nicotinic receptors already at therapeutic concentrations.

Zyban Mechanism of action

Zyban – thanks to its mechanism of action – is able to reduce nicotine cravings in patients, also reducing the discomfort and symptoms induced by abstinence. Furthermore, the drug is able to reduce the risk of relapse.

Bupropion Dosage

Zyban dosage must be established by the doctor on an individual basis. In any case, the dose of drug normally used is 150 mg of active ingredient, to be taken once a day. The dose can be increased up to 300 mg. In patients with hepatic and / or renal insufficiency a reduction in the dose of bupropion administered may be necessary. Although no cases of withdrawal symptoms have been reported, abrupt termination of therapy is not recommended; instead, a gradual reduction of the dose is recommended.

Zyban Directions

Zyban should be taken by mouth, at the doses indicated by the doctor. Do not increase the number of tablets taken every day and do not extend the treatment beyond the prescribed period. It usually takes 1-2 weeks for the drug to fully develop its effectiveness, so treatment should not be interrupted too soon if no improvement is observed.

Store the drug at room temperature, in a cool, dry place away from light. Do not use the drug if the label indicates that it has expired. Keep it away from children. Store the medicine in the original package together with the package insert.

Zyban vs Wellbutrin – which is better?

zyban-vs-wellbutrinWellbutrin is a medicine prescribed by your doctor to treat your depression. It is thought to interact with chemicals in the brain called noradrenaline and dopamine, which are linked to depression. The active ingredient is bupropion hydrochloride. Each tablet contains wellbutrin dosage 150 mg or 300 mg of bupropion hydrochloride.

It is up to your prescriber to determine which of the two medications is best for you, proceeding from a) response to therapy and b) susceptibility towards side effects of either of the drugs.

Zyban vs Zoloft – what to choose?

Zoloft (sertraline) is an antidepressant drug belonging to the selective serotonin reuptake inhibitor class. Furthermore, sertraline also has a weak action on the re-uptake of noradrenaline and dopamine. The use of sertraline is indicated for the treatment of:

  • Depression;
  • Social anxiety disorder;
  • Panic attacks, phobias;
  • PTSD;
  • OCD.

The use of bupropion is limited to the treatment of major depressive disorder, so its application is limited to this specific subpopulation. However, Zyban online is also appointed in patients fighting nicotine addictions.

What is the difference between Zyban and Champix?

Champix (varenicline) is a drug with specific indications to help patients stop smoking. Champix represents an alternative to the use of other drugs used to combat smoking addiction, such as Zyban and nicotinic replacement therapy.

Some studies have shown that Champix may be more effective than Zyban in smoking cessation therapy and relapse prevention. However, you should rely on prescriber’s opinion when choosing your quit-smoking drug.

Zyban vs Chantix

Chantix (varenicline) is a full analog of Champix, the drug described in the paragraph above. When compared to Zyban and its application, they are used interchangeably, with Chantix effects for smoking cessation being more promising but less studied. However, while Zyban is also used in depression disorder treatment, Chantix is strictly a nicotine dependence drug whose use is limited to helping in quitting smoking.

Zyban Side effects

In addition to the expected health effects, Zyban can cause the onset of certain side effects. This drug is generally well tolerated; however, sometimes disorders such as: dizziness, nausea, diarrhea, stomach pain, headache, agitation, insomnia or drowsiness and tingling in the limbs may occur. Tell your doctor if you have any other problems while taking the medicine. Tell your doctor if you have any other complaints due to taking the medicine.

Zyban Precautions

bupropion-150mgSome side effects can be enhanced by alcoholic beverages which should therefore be avoided.

If you are taking other anxiolytics containing substances called “benzodiazepines” you should not immediately stop using it (unless otherwise advised by your doctor), since this drug is not effective before ten days.

Report the medications you are taking; if you have serious kidney or liver or other organ diseases; if you have suffered in the past from “allergies” to drugs or diseases such as eczema, asthma, hives.

Report if a work activity is taking place that involves particular dangers and requires a particularly intense state of attention.

(For patients): Report if you are pregnant or breast-feeding or if a pregnancy is possible.

Zyban Contraindications

You should not take other drugs with sedative effects concomitantly with Zyban, for instance medications for allergies (antihistamines), products to treat cold symptoms, pills for insomnia and other drugs that the doctor or pharmacist will be able to indicate.

Priligy

 

What is Priligy?

Priligy (dapoxetine) is a premature ejaculation (PE) medication administered orally. Up to date, Priligy is the only a delaying pharmacological response, Priligy, a systemic drug administered orally with action in the central nervous system based on dapoxetine, a molecule that belongs to the class of drugs used as antidepressants (SSRI inhibitors, selective serotonin reuptake inhibitors). The drug is taken on demand, which means before a sexual activity is planned.

Priligy Mechanism of Action

Premature-ejaculation-treatmentDapoxetine, the active component in Priligy, is a SSRI designed specifically for premature ejaculation. Researchers at the University of Minnesota in U.S.A. published in the prestigious scientific journal Lancet a work with which they tested the effectiveness of dapoxetine. The study involved 2600 men, of whom 870 received placebo, 874 a dose of 30 mg dapoxetine and 870 a dose of 60 mg. Ejaculation times went from one minute and 75 seconds for men who took placebo to three minutes and 32 seconds of those who had taken dapoxetine at a dose of 60 mg.

Recent scientific studies link premature ejaculation to a serotonin deficiency and justify the use of SSRI antidepressants. This type of drugs – together with tricyclics, however considered less relevant than the former – is today effective in the pharmacological treatment of premature ejaculation, even if their side effects often do not justify the benefits of this solution.

As is known, premature ejaculation can be treated both at a therapeutic and psychological level, with psychological support from an expert in psychosexual problems, and at a pharmacological level.

The pharmacological treatment involves the use of antidepressant drugs such as SSRIs, and, in the most difficult cases or in the case of non-improvement with the first type of antidepressants, the use of tricyclic drugs which however contain a greater risk from the point of view of side effects.

How to take Priligy

A tablet of Priligy is taken on demand, 30 to 60 minutes before the planned sexual activity. A tablet should be taken as a whole with sufficient amount of water. Never take more than one recommended Priligy dose; do not combine the drug with alcohol.

How long do effects of Priligy last?

Dapoxetine half-life is 2 to 3 hours. Dapoxetine should be taken an hour and a half before sexual intercourse. As a result, patients can usually expect the ejaculation time to double.

Contraindications and precautions

Priligy is contraindicated against the background of the following health conditions:

  • bipolar disorders
  • history of mania or depression
  • history of drug abuse
  • renal insufficiency
  • hepatic insufficiency

This list is incomplete and is a subject to elaboration by certified doctor.

The long elimination half-life of both dapoxetine and norfluoxetine should be kept in mind with pharmacodynamic or pharmacokinetic type interactions (eg changing from dapoxetine to other antidepressants) should be considered. Combinations with irreversible, non-selective monoamine oxidase inhibitors (eg iproniazid) are prohibited: sme cases of severe and sometimes lethal reactions have been reported in patients treated with an SSRI in combination with an irreversible, nonselective monoamine oxidase (IMAO) inhibitor. These cases presented similar characteristics to the serotonin syndrome (which can be confused with (or diagnosed as) malignant neuroleptic syndrome). Ciproeptadine or dantrolene may help patients with these reactions.

Priligy Side Effects

Side effects such as nausea, diarrhea, headache and dizziness given by Priligy are mild and transient. High efficacy in combination with low side event profile makes Priligy an optimal drug for the treatment of premature ejaculation.

Cialis and Dapoxetine

Dapoxetine-60-mgCialis Super Force is a combination drug containing tadalafil citrate and dapoxetine. The use of this combination of drugs is justified in subjects whose PE problem is aggravated or even caused by another sexual disorder, erectile dysfunction (ED). Tadalafil (Cialis) is used to treat ED, the efficacy of the substance lasting for approximately 36 hours.

Given that SSRI are reported to have detrimental effect on erectile function, Cialis and dapoxetine can be used concomitantly in order to prevent the onset of ED symptoms.

Levitra with Dapoxetine

Levitra (vardenafil) is yet another ED drug, but unlike Cialis, it has a milder and less durable effect whose half-life is closer to that of dapoxetine. The use of this combination therapy is advisable in men suffering from both ED and PE or against the background of particular susceptibility towards debilitating effects of dapoxetine on erectile function.

Super P Force

Super P Force is a combinatory drug containing dapoxetine and sildenafil, the main ingredient in Viagra, which was the first ED drug to be presented on the pharmaceutical market, and until present day remains one of the best-studied and impactful drugs aimed at symptomatic relief of ED. Used alongside each other, sildenafil and dapoxetine make for an ultimate sexual enhancer.

Sildenafil can also be used as part of PE treatment in subject suffering from PE linked to compromised erectile ability and associated performance anxiety.

Premature ejaculation treatment

The use of drugs for premature ejaculation capable of delaying the male orgasm and thus lengthening the duration of sexual intercourse is a very hot topic for both the patient and the doctor, but it is also much debated in the medical profession. Some specialists believe that drugs are not necessary for treating the disorder because, according to them, the precociousness of ejaculation is the consequence of psychological anxieties and fears and because possible side effects could overcome the hoped for therapeutic benefits.

Other doctors, on the other hand, are in favor of using specific drugs because they are convinced that their administration – regardless of the cause of the ejaculatory disorder – may produce benefits not only on the anxiety and worry that afflict the patient at the time of the sexual act but also on the control of ejaculation.

However, it must be emphasized that each individual responds in an own and unique manner to excitatory stimuli, so that if a man can overcome the problem by consulting only with the specialist, another can instead request the administration of drugs with an “immediate” effect for to cure this sexual disorder.

Since various researches suggest that the ejaculatory precocity is due to functional deficits of some substances very important for the functioning of the brain and nervous system, one of which is serotonin, one of the treatments used for premature ejaculation is based on the administration of drugs capable of correcting the action of serotonin, thus prolonging the duration of sexual intercourse; these are usually so-called anti-depressants. Not surprisingly, in fact, a side effect of these drugs (exploited therapeutically in these cases) is precisely the ejaculatory delay. However, other side effects of these unwanted and annoying drugs are nausea, dry mouth, drowsiness and, paradoxically, a drop in libido.

Where to buy Priligy online

Generic Priligy is a prescription drug with a certain number of contraindications that pose serious health risks when ignored or when the drug is acquired by circumventing existing prescribing instructions. Remember that self-diagnosing and self-medicating risks far outweigh possible benefits, therefore consulting a certified physician, urologist or andrologist is a necessary condition to buy Priligy online.

Generic Priligy is available in a large number of online pharmacies. It is important to choose an e-commerce drug supplier with utmost care. It is necessary to make sure that the pharmacy provides high quality medications whose content corresponds to industry’s standards. Ordering Priligy with home delivery should not take more than several minutes, but will be considerably more economical thanks to generally lower cost of items purchased online, pharmacy drugs including.

Priligy analogs

buy-priligy-online

  • Poxet – Sunrise Remedies
  • Priligy – Johnson & Johnson
  • Dapolast – Micro Labs Ltd.
  • Dapox – Ranbaxy Laboratories Ltd.
  • Dapoxy – Alembic Ltd.
  • Justinex – Emcure Pharmaceuticals Ltd.
  • Prilyxet – Sun Pharma Laboratories Ltd.