Basic Drug Info

Manufacturer:

Fortune Healthcare Pvt. Ltd.

Active Substance:

Tadalafil

Drug Form:

Film-coated tablets

Available Doses:

20mg

Product

Price Per pill Order

Tadalista®.2.5mg x 20 tablet

€43.49€2.17Buy

Tadalista®.2.5mg x 32 tablet

€49.71€1.55Buy

Tadalista®.2.5mg x 60 tablet

€68.37€1.14Buy

Tadalista®.2.5mg x 92 tablet

€95.32€1.04Buy

Tadalista®.2.5mg x 120 tablet

€108.80€0.91Buy

Tadalista®.2.5mg x 180 tablet

€139.90€0.78Buy

Product

Price Per pill Order

Tadalista®.5mg x 30 tablet

€51.78€1.73Buy

Tadalista®.5mg x 60 tablet

€77.70€1.30Buy

Tadalista®.5mg x 90 tablet

€103.62€1.15Buy

Tadalista®.5mg x 120 tablet

€113.99€0.95Buy

Tadalista®.5mg x 180 tablet

€149.23€0.83Buy

Product

Price Per pill Order

Tadalista®.10mg x 30 tablet

€56.97€1.90Buy

Tadalista®.10mg x 60 tablet

€93.25€1.55Buy

Tadalista®.10mg x 90 tablet

€108.80€1.21Buy

Tadalista®.10mg x 120 tablet

€124.35€1.04Buy

Tadalista®.10mg x 180 tablet

Free shipping

€167.89€0.93Buy

Product

Price Per pill Order

Tadalista®.20mg x 30 tablet

€62.15€2.07Buy

Tadalista®.20mg x 60 tablet

€103.62€1.73Buy

Tadalista®.20mg x 90 tablet

€129.54€1.44Buy

Tadalista®.20mg x 120 tablet

€145.09€1.21Buy

Tadalista®.20mg x 180 tablet

Free shipping

€186.55€1.04Buy

Product

Price Per pill Order

Tadalista®.40mg x 30 tablet

€72.52€2.42Buy

Tadalista®.40mg x 60 tablet

€124.35€2.07Buy

Tadalista®.40mg x 90 tablet

Free shipping

€163.75€1.82Buy

Tadalista®.40mg x 120 tablet

Free shipping

€186.55€1.55Buy

Tadalista®.40mg x 180 tablet

Free shipping

€233.21€1.30Buy

Product

Price Per pill Order

Tadalista®.60mg x 30 tablet

€93.25€3.11Buy

Tadalista®.60mg x 60 tablet

€155.45€2.59Buy

Tadalista®.60mg x 90 tablet

Free shipping

€186.55€2.07Buy

Tadalista®.60mg x 120 tablet

Free shipping

€217.66€1.81Buy

Tadalista®.60mg x 180 tablet

Free shipping

€279.86€1.55Buy

What is Tadalista?

improve-erectile-function

Tadalista (active substance tadalafil citrate) is a drug used orally as needed before planned sexual activity in order to retrieve the lost or compromised ability to develop erectile hardness in response to sexual stimulation.

Tadalista is a generically produced version of tadalafil, which is universally recognized under the brand name of Cialis, the “weekend pill”. The drug’s moniker derives from its outstanding phacmacodynamic feature of supreme efficacy window that lasts for 36 hours after the moment of effect onset.

Tadalista and Cialis are interchangeable in the majority of instances, when the dosage coincides (the former is available in a single dose of tadalafil 20mg, while the original preparation dosage range is more diversified and comprises of 2.5mg, 5mg, 10mg and 20mg pills).

How does Tadalista work?

Tadalista is an oral drug used to improve erectile function by enhancing the effect of nitric oxide (NO), the main mediator of penile erection. Tadalista is one of the class of drugs called inhibitors phosphodiesterase type 5. These drugs, in fact, by inhibiting the enzyme phosphodiesterase 5 (PDE5), cause the relaxation of the smooth muscle cells of the penis to be amplified, guaranteeing a more rigid and lasting erection.

By inhibiting PDE5, sildenafil, vardenafil and tadalafil obtain the effect of amplifying the action of NO and therefore enhancing the physiological mechanism of erection. The PDE5i, therefore, do not directly induce an erection, but rather optimize the mechanism in the presence of a physiological stimulus. Therefore, for PDE5i to work, there must be at least a minimal endogenous production of NO. The mechanism of action is similar for all three drugs, which have shown in important clinical studies to be effective and well tolerated.

Who manufactures Tadalista?

Tadalista is manufactured in India by a certified pharmaceutical company Fortune Healthcare Pvt. Ltd. with years of expertise in generic drug manufacture. Being a generic equivalent of the world’s best selling drug, Tadalista costs significantly less than the original drug. The rationale behind the drug’s affordability is the price formation rules for generic drugs, which include the cost of production and logistics (the original drug prices also incur the investments in the research and promotion phase).

How long does tadalafil take to work?

efficacy-of-PDE5

The response window for tadalafil is estimated between 30 and 40 minutes, but in practice the onset time is affected by a number of factors which can both speed it up or delay it. These are:

  • the timing of the last meal taken
  • the presence / absence of alcohol in the blood plasma
  • patient’s age
  • patient’s physique and fitness level
  • general health condition of the patient
  • concomitant use of certain other drugs

How safe is Tadalista?

Tadalista is a high quality generic medication produced in accordance to ISO 9000:2001 and Good Manufacturing Practice guidelines that ensure the safety of the final product. As for the active substance of the drug, tadalafil, its safety in both short-term application and long-term use have been proven by dozens of patient-years. You can find the results of tadalafil safety studies here.

During the years of tadalafil existence, millions of patients around the world have taken the drug in its brand and generic forms, demonstrating in the field that they are safe drugs, even if they are taken repeatedly over the long term, as long as the warnings and contraindications on the package insert are respected. Although the efficacy and safety profile of PDE5i are optimal, their use must take place under the guidance and control of a specialist doctor.

Is tadalafil Viagra?

Viagra, the first PDE5 inhibitor, was introduced on the market in 1998. Viagra contains the active substance sildenafil. In the following years two other drugs were added: vardenafil and tadalafil.

The duration of action, ie the time frame in which the erection will be facilitated and improved, varies with the three different drugs depending on their half-life, but is however strongly variable from one patient to another. In any case, in subjects who respond to therapy, the duration is never less than 4 hours, and with the drug with longer half-life (tadalafil) it can exceed 36 hours.

PDE5 inhibitors are today the first therapeutic choice in almost all forms of erectile dysfunction, effective and well tolerated in over 70% of ED cases. Obviously, not all cases of erectile dysfunction are the same. We know that ED can be of different etiology and severity, and the efficacy of PDE5 can vary in different categories of patients. However, there is no form or type of erectile dysfunction in which PDE5 inhibitors are not effective, at least in a minority of patients. For this reason, whatever the type of ED, most specialists consider other treatment options only after these oral medications have proven ineffective.

Tadalafil side effects

The undesirable effects of tadalafil are similar to those of other phosphodiesterase inhibitors: during the studies headache, flushing of the face, back pain, dyspepsia, nasal congestion, nausea, abdominal pain, dizziness, myalgia were reported more frequently. Undesirable effects are dose-dependent and predominantly mild. At the moment the data are insufficient to assess long-term undesirable effects in groups of patients with high cardiovascular risk. The undesirable effects are closely related to the mechanism of pharmacological action of inhibition of phosphodiesterase type 5. This isoenzyme is not present exclusively in the corpora cavernosa, although it is predominant here, and also intervenes in other metabolic pathways. Furthermore, due to the inhibitory activity on PDE 6, which is found in high concentration in the retinal cells, visual disturbances may occur even if with low frequency. Like sildenafil, tadalafil also has the potential to decrease blood pressure, which could be a problem in patients treated with antihypertensives.

Precautions

By intervening on the NO / cGMP metabolic cycle, vardenafil enhances the hypotensive effect of nitrates and its administration is contraindicated in patients who are taking nitrates in any pharmaceutical formulation. It is also contraindicated in patients with recent history of stroke and heart attack and, for possible vision disorders, even in patients with degenerative retinal diseases such as retinitis pigmentosa. Tadalista should not be used in patients with severe hepatic impairment.

Contraindications

pharmacological-substance

Clinically relevant hypotension may occur in patients taking non-selective alpha blockers. Interactions with any drug inhibitor of the CYP3A4 enzyme system (eg erythromycin, azole antifungals, indinavir) are possible. There are no interactions with food and alcohol.

Tadalista should not be used in individuals suffering from:

  • heart disease
  • high blood pressure
  • low blood pressure
  • ulcerative disease of stomach or duodenum
  • renal or hepatic dysfunctions
  • retinitis pigmentosa, NAION
  • Peyronie’s disease, Priapism
  • sickle cell anemia, leukemia, multiple myeloma

Verify the full list of Tadalista contraindications with your prescriber and keep them informed about your past and current medical conditions, as well as give them a full list of pharmacological substances (prescription, OTC and food supplements) you are currently using.

Where to get Tadalista?

In the US and other countries where the patent for exclusive production of Cialis has not yet expired, Tadalista is available for sale exclusively online. Note that Tadalista is a prescription drug that requires medical consultation and approval before you order Tadalista online; however, multiple services operating as international pharmacies offer free medical consultations online by board-certified doctors.

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Customer reviews

By Ethan,

Saturday 30th of November 2019

Cialis vs Viagra: I’m new to ED drugs, how do I choose? I am a 48yo man with no major problems with health. I am a smoker and was recommended quitting as the most important step to fight my ED. My erections have been limp for a long while now, and sometimes I cannot get it up at all. What is the best drug for my condition? My prescriber says it is safe for me to take either. Thank you.

By James Daniels M.D

Monday 2nd of December 2019

Dear Ethan, I can whole-heartedly second your doctor: you need to revise your lifestyle habits. Admittedly, it is easier said than done, but the rewards in your general health and sexual health in particular will be well worth the trouble. As for your main question, Viagra and Cialis are the drugs that belong to the same class and have identical mechanism of action. Some users respond better to sildenafil contained in Viagra, while it is tadalafil (Cialis) that gets the job done for others. You need to try both in order to establish which of the substances work best for you specifically. Be advised that both medications have been around long enough to make it safe saying that they can be used safely with minimal if any side effects, even in the long run. When facing the classical Viagra vs Cialis dilemma, you should proceed from your lifestyle circumstances: Cialis works best for men who engage in sex often, as it remains active during 36 hours, so with a couple of pills weekly you will be able to have uninterrupted sex life. Cialis is also available in every-day doses, which has proven efficacy in eliminating the ED problem for good. Viagra has its benefits: its shorter halflife makes its side effects less noticeable, and many notice that its effects are more targeted and impactful. Viagra is your number one choice if you have sex only occasionally. Remember that it is your prescriber who needs to appoint the initial dose and adjust it if needed. Also, never take two ED drugs within 24 hours’ period.

By Eugene,

Tuesday 28th of January 2020

I tried 20 mg Tadalista… I practically had a relationship with two girls at the same time… each one didn’t know about the other. Being single and not particularly sexually active prior to that I did not want to miss such an opportunity and therefore, I chose to try with the “help” above to ensure excellent performance and not to disappoint either of them… The effect is decidedly strong but it is not true that you are walking around with a hardon, it reacts only when there is stimulation and the recovery times between one coitus and the other are very short.

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